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Ms Shalu Jhajra wins Best Poster Award at the Drug Metabolism and Discovery ADMET India 2014 conference
Ms Shalu Jhajra wins Best Poster Award at the Drug Metabolism and Discovery ADMET India 2014 conference

Nelfinavir is an antiretroviral drug, which belongs to protease inhibitors and is used widely in combination with other HIV reverse transcriptase inhibitors for the treatment of human immunodeficiency virus (HIV) infection. The FDA drug information document shows that nelfinavir's 1950 mg BID regimen results in discontinuation of drug due to toxicity in 9% patients'. The reason behind the toxicity is yet to be explored.
Poster
Application of Tandem Mass Spectrometry in Identification of 35 Trace Metabolites of Nelfinavir Mesylate in Human Liver Microsomes
Application of Tandem Mass Spectrometry in Identification of 35 Trace Metabolites of Nelfinavir Mesylate in Human Liver Microsomes
Shalu Jhajra and Saranjit Sigh
Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S.A.S. Nagar, Punjab, India
Poster Views: 3,412
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Poster Abstract
Nelfinavir is an antiretroviral drug, which belongs to protease inhibitors and is used widely in combination with other HIV reverse transcriptase inhibitors for the treatment of human immunodeficiency virus (HIV) infection. The FDA drug information document shows that nelfinavir's 1950 mg BID regimen results in discontinuation of drug due to toxicity in 9% patients'. The reason behind the toxicity is yet to be explored.

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