Polymorphism and Crystallization Conference
Royal Sonesta Boston, 40 Edwin H Land Boulevard, Cambridge, 02142, United States
08 April 2019 - 09 April 2019Summary
Chemical Development IssuesOverview
The reproducible production of organic crystals in the correct form (habit, solvate, polymorph) and particle size is a source of much heart-ache to chemists, engineers, pharmacists and formulators. Although production of new polymorphs and solvates can be a source of profit for companies through extension of the patent lifetime, the inability to manufacture a consistent crystalline form often leads to costly project delays, particularly in chemical development.
This conference will focus on these issues from the viewpoint of the process chemist and chemical engineer; i.e. on chemical development issues which impact the ability to routinely manufacture the chosen crystalline form, whether this be the most stable or a metastable crystal. Case studies from different companies will show how different organisations identify and solve these extremely difficult issues in different ways, depending on how far the project is along the development time line. Experts in the field will also give lectures on problem solving and troubleshooting, as well as giving insight into new techniques (supercritical fluids, polymorph prediction, etc), which will be of value in the future.
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