Abstract: Objective：The prevalence of abnormal glucose metabolism in the population is increasing year by year, and obstructive sleep apnea (OSA) is closely related to cardiovascular and metabolic diseases. The current research suggests that abnormal glucose metabolism and OSA often co-exist. The co-morbidity of OSA and abnormal glucose metabolism often increases the risk of stroke. However, the risk factors associated with the disease have not been adequately studied. The prevalence of OSA with glucose metabolism abnormalities at different body mass indexes (BMI) has been poorly reported. The purpose of this study was to investigate the co-morbidity prevalence of OSA and glucose metabolism abnormalities in community residents at different body mass indexes, so as to provide evidence for disease prevention. Methods：The study adopted a whole-group sampling method to collect questionnaires from 1270 residents aged 35-75 years in the Tianshan community of the city of Karamay, while anthropological measurements were collected on the basis of which body mass index was further calculated. Glucose metabolic status was assessed by medical history and intravenous fasting glucose. Sleep apnoea was analysed based on portable polysomnography monitoring data, with a diagnostic threshold of oxygen descent index (ODI) ≧ 5 times/hour. Data were analysed using spss20.0. Results：Among 1270 respondents, 1178 completed all the surveys, with a total effective rate of 92.76%.Among the community residents aged 35-75 in Karamay, the number of people with BMI < 18.5(low body weight) accounted for 1.26%, the number of people with 18.5≤BMI < 24 (normal body weight) accounted for 26.80%, the number of people with 24≤BMI < 28 (pre-obesity) accounted for 41.42%, and the number of people with BMI ≥ 28 (obesity) accounted for 30.51%.At the cut-off point of ODI ≥ 5 times/hour, the co-incidence rate of type 2 diabetes and OSA in the patients with low BMI was 0.00%.The co-incidence rate of type 2 diabetes and OSA was 2.45% in patients with normal BMI.The comorbidities of type 2 diabetes and OSA were 5.06% in those with pre-obesity BMI and 5.93% in those with BMI obesity.The chi-square test showed that the co-incidence rate of type 2 diabetes and OSA among the four groups had statistical difference (P<0.05). Conclusion：As body mass index increases, the prevalence of type 2 diabetes and OSA increases separately, and the co-morbidity of type 2 diabetes and OSA also increases. Body mass index is an important risk factor for abnormal glucose metabolism and obstructive sleep apnoea. The number of pre-obese and obese people in this community is relatively large. Health education on diabetes and sleep apnoea should be increased to improve the health management of patients with diabetes and OSA, and appropriate prevention and treatment strategies should be developed according to their prevalence in Karamay to minimise the prevalence and risk of cardiovascular diseases and metabolic diseases.Summary: A survey of co-morbidity of type 2 diabetes and sleep apnea among community residents with different body mass indexes
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Effects of chronic intermittent hypoxia/reoxygenation on body weight and glucose metabolism in rats
Comprehensive one-stop platform to accelerate research
Chemokine Signaling Pathway
ROLE OF LEPTIN IN TREATING METABOLIC DISORDERS
Health vision 2030: An Era of Evolution and Revolution in India