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A Correlative Study of CRP and C3 complement element in Women with Polycystic Ovarian Syndrome
Poster Title: A Correlative Study of CRP and C3 complement element in Women with Polycystic Ovarian Syndrome
Submitted on 19 Sep 2021
Author(s): Mr. Indra Prasad Adhikari
Affiliations: index medical college
This poster was presented at online
Poster Views: 194
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Poster Information
Abstract: Objective: To evaluate the role of CRP and C3 in Women with PCOS factors related to pathogenesis of PCOS.
Materials and Methods: This was a hospital-based cross-sectional prospective study carried out among PCOS was conducted in the Department of Obstetrics & Gynecology, Index Medical College Hospital & research center , Indore, M.P. The study duration was two years. A total of 260 subjects with age groups between 15 to 45 years were divided into cases and controls.
Results: Among a total of 260, 130 were diagnosed with PCOS, and 130 were healthy women based on clinical and different biochemical parameters, The mean ±SD of various parameters among PCOS cases were; BMI 32.97±8.466, TC 188.42±31.126, TG 134.43±50.01, HDL 36.29±9.55 TC/HDL ratio, 5.54±1.865 serum CRP, 3.41±0.94 C3, 160.66±29.155 versus BMI 22.87±2.470, TC 155.42±26.333, TG 110.00±42.19, HDL 41.22±10.912, TC/HDL ratio 4.08±1.39, serum CRP 2.25±0.8 c3, 127.48±35.60 in healthy control.
Conclusion: In this study, the role of CRP, C3, and different biochemical parameters were studied among PCOS cases and control. It was found that a majority of the PCOS patients had increased levels of CRP, C3, and other biochemical parameters. The levels of C3, CRP as a marker of chronic low-grade inflammation were higher in PCOS as compared to the controls. The C3 values correlated well with an increase in BMI, marital status, age hirsutism.
Summary: Polycystic ovarian syndrome (PCOS) is a common endocrine disorder in women of the reproductive age characterized by chronic oligomenorrhea, amenorrhea, anovulation, obesity, hirsutism, hyperandrogenism, and numerous follicular cysts in enlarged ovaries. Global and in India the prevalence rate of PCOS is 7% and approximately 4-11% respectively, in women with reproductive age group.References: Report abuse »
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