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A NOVEL PAPER BASED TECHNOLOGY FOR BIOSAMPLE COLLECTION AND BIOBANKING
EP24807
Poster Title: A NOVEL PAPER BASED TECHNOLOGY FOR BIOSAMPLE COLLECTION AND BIOBANKING
Submitted on 22 Nov 2016
Author(s): Stephanie Pigeot-Rémy2, Noel Cartier2, Tonia Showers2, Kurt Langenbach3, Michael E. Hogan1, Kaiwan Chear1, Kelechi Anoruo1, Shanavaz Nasarabadi1
Affiliations: 1. R&D, GenTegra LLC, Pleasanton, NY, United States. 2. Advanced Liquid Technologies, Ahlstrom, Pont-Evêque, France. 3. Custom Services, ATCC, Manassas, VA, United States.
This poster was presented at ISBER 2016
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Poster Information
Abstract: Biological samples, in particular whole blood have been field collected and stored in biobanks on filter paper cards for decades. Although the current filter paper technologies (Whatman FTA, 903) have been the media of choice for storing blood DNA, such dried blood spots (DBS) are resistant to full recovery and, more importantly, need to be purified before use, as the FTA chemicals inhibit protein and nucleic acid biochemistry. With DARPA support, GenTegra has developed a new class of chemically treated innovative paper, for stabilizing the DNA (GenSaver™ DNA cards), RNA (GenProtect™ RNA cards) and protein complement of whole blood. We have initiated DBS studies for whole blood and saliva to demonstrate DNA stabilization for >10yrs. In parallel, the HIV-1 and dengue virus (and host) complement of whole blood have been studied for RNA virus stabilization.Summary: A new technology in collection cards that allow field collection of DNA and RNA samples and transport safely at ambient temperatures. The Active Chemical Protection added to the paper matrix also allows storage of DNA samples for >20 years, also at ambient temperatures.Report abuse »
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