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ABC Transporters Family
Poster Title: ABC Transporters Family
Submitted on 18 Nov 2021
Author(s): Marcia Brady
Affiliations: Creative Biogene
This poster was presented at Creative Biogene
Poster Views: 161
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Poster Information
Abstract: ABC (ATP‑binding cassette) proteins form one of the largest and most diverse protein superfamilies, whose members can be found in all eukaryotic and prokaryotic organisms studied to date. The most of ABC proteins are transporters that translocate allocrites across biological membranes. Almost half of the 48 human ABC transporter proteins are thought to facilitate the ATP-dependent translocation of lipids or lipid-related compounds. Such substrates include cholesterol, plant sterols, phospholipids, bile acids and sphingolipids. Mutations in a substantial number of the 48 human ABC transporters have been related to human disease
Summary: ABC transporters are transmembrane proteins that utilize the hydrolysis of ATP to facilitate the movement of a wide variety of substrates across membrane bilayers. There are more than 250 members in the ABC superfamily that can be thought of as importers or exporters. Report abuse »
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