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ANTIBODIES FOR CORONAVIRUSES
EP32925
Poster Title: ANTIBODIES FOR CORONAVIRUSES
Submitted on 21 Aug 2020
Author(s): Creative Biolabs
Affiliations:
This poster was presented at https://www.creativebiolabs.net/
Poster Views: 95
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Poster Information
Abstract: Based on the previous studies, coronaviruses are enveloped viruses, both
the receptor binding and the membrane fusion process of which are
mediated via the spike (S) membrane glycoprotein. Therefore, the crossreactivity
of anti-SARS-CoV antibodies with SARS-CoV-2 spike protein
could have important implications for the rapid discovery and
development of vaccines and therapeutic antibodies against SARS-CoV-2.
The SARS-CoV-specific human monoclonal antibody, CR3022, could bind
potently with SARS-CoV-2 RBD (KD of 6.3 nM). The epitope of CR3022
does not overlap with the ACE2 binding site within SARS-CoV-2 RBD.
Therefore, CR3022 has the potential to be developed as candidate
therapeutics, alone or in combination with other neutralizing antibodies,
for the prevention and treatment of SARS-CoV-2 infections. https://www.creativebiolabs.net/search?key=SARS-CoV-2%2520(2019-nCoV)&ty=product&cid=0
Summary: Based on the previous studies, coronaviruses are enveloped viruses, both
the receptor binding and the membrane fusion process of which are
mediated via the spike (S) membrane glycoprotein.
References: https://www.creativebiolabs.net/resource/pdf/com/brochure/Antibodies-for-Coronaviruses.pdfReport abuse »
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