Abstract: In the dosage form, the API is in direct contact with other components (excipients) in the formulation, thus facilitating drug administration and release and protecting it from environmental impacts.Summary: Preformulation is a crucial phase in drug development in which the physicochemical profiling of active pharmaceutical ingredients (APIs) and excipients is determined and prototype formulations made. References: https://www.formulationbio.com/api-excipient-compatibility.html
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