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Are we missing the opportunity to measure muscle mass on CT thorax?
Poster Title: Are we missing the opportunity to measure muscle mass on CT thorax?
Submitted on 07 Nov 2019
Author(s): B. Bryl, S. Merrix, D. Proud, A. Marin, A. Byrne, J. Duckers1
Affiliations: All Wales Adult Cys=c Fibrosis Centre, University Hospital of Llandough, Cardiff, CF64 2XX, UK
Poster Views: 452
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Poster Information
Abstract: Hand grip strength (HGS) and fat free mass index (FFMI) are important indicators of skeletal muscle mass and therefore prognosis in patients with respiratory diseases including cystic fibrosis (CF)1,2. CT’s have become gold standard in assessing lean body mass (LBM) in cachexia in other diseases including cancer. It provides accurate information regarding muscle mass and adipose tissue allowing for singular or longitudinal assessments over time2. This information can be used to improve our understanding of LBM and its correlation with lung function and patient outcome. We propose that calculating muscle volume and density on CT imaging would correlate strongly with FFMI and HGS. This could provide important information to centres where HGS and FFMI testing is lacking and provide prognostic value in CF patients.
Summary: Aims
Identifying a correlation between muscle volume and density on CT images with;
Lean Body Mass (LBM)
Hand Grip Strength (HGS)
Fat Free Mass Index (FFMI)
Lung Function
References: Bahat G, Turfan A, Ozkaya H et al. Relation between hand grip strength, respiratory muscle strength and spirometric measures in male nursing home residents. Aging Male. 2014 Sep;17(3):136-40.
Schols AMWJ, Broekhuizen R, Weling-Scheepers CA, Wouters EF. Body composition and mortality in chronic obstructive pulmonary disease. The American Journal of Clinical Nutrition. 2005 July;82(1):53-59.
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