« Back
ATP-binding Cassette (ABC) Transporter
Poster Title: ATP-binding Cassette (ABC) Transporter
Submitted on 23 Oct 2020
Author(s): Hannah Cole
Affiliations: Creative Bioarray
This poster was presented at creative bioarray
Poster Views: 48
View poster »

Poster Information
Abstract: Drug-drug interactions (DDI) are severe drug-induced side effects. The occurrence of drug–drug interactions is due to the effects of drugs on uptake and efflux transporters, which can be roughly divided into two categories: induction and inhibition. Drug transporters that distribute in small intestine, liver, and kidney are determinants of the pharmacokinetic profile of drugs. Transporter-mediated DDI in these three organs can considerably influence the pharmacokinetics and clinical effects of drugs.
Summary: Drug transporters mediate the uptake and efflux of a broad variety of drugs and drug metabolites. Most uptake transporters are members of the solute carrier (SLC) family, while most efflux transporters are members of the ATP-binding cassette (ABC) transporter family.Report abuse »
Ask the author a question about this poster.
Ask a Question »

Creative Commons