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Bioluminescent Metabolite Assays Enable Easy Measurement of Changes in Tumor Biology
EP25779
Poster Title: Bioluminescent Metabolite Assays Enable Easy Measurement of Changes in Tumor Biology
Submitted on 15 May 2017
Author(s): Michael P. Valley, Donna Leippe, Mary Sobol, Natasha Karassina, Sarah Duellman, James J. Cali, and Jolanta Vidugiriene
Affiliations: Promega Corporation, 2800 Woods Hollow Rd, Madison, WI 53711
Poster Views: 1,107
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Poster Information
Abstract: Tumor cells rely on metabolic reprogramming to meet their increased demands for energy and biomass. Such reprogramming is exemplified by increased rates of glucose uptake, greater utilization of glycolysis, and a reliance on glutaminolysis. We have developed a suite of bioluminescent assays that can monitor metabolites in all of these important pathways.Summary: Tumor cells rely on metabolic reprogramming to meet their increased demands for energy and biomass. Such reprogramming is exemplified by increased rates of glucose uptake, greater utilization of glycolysis, and a reliance on glutaminolysis. We have developed a suite of bioluminescent assays that can monitor metabolites in all of these important pathways.References: Report abuse »
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