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Clinical helpfulness of F-18 FDG PET/CT imaging in diabetic patients with malignant otitis externa
Poster Title: Clinical helpfulness of F-18 FDG PET/CT imaging in diabetic patients with malignant otitis externa
Submitted on 09 Sep 2018
Author(s): Muhammad Umar Khan, Jawaher Al-Ajmi, Zuhair Saleh Abdullah, Sunil Kumar Kodali
Affiliations: Department of Nuclear Medicine, Al-Jahra Hospital, Kuwait
This poster was presented at BIR Annual Congress 2018
Poster Views: 968
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Poster Information
Abstract: Introduction:
Malignant Otitis Externa (MOE), a commonly observed severe infection of external auditory canal and skull base in diabetic patients pose a clinical challenge and warrants prompt treatment. We present a case series highlighting the clinical utility of F-18-Fluoro-2-deoxy-D-glucose (FDG) PET/CT imaging in these scenarios.
Eight PET/CT imaging studies were performed on seven female diabetic patients, referred to the department, Al-Jahra Hospital Kuwait consecutively from 08/2014-10/2017, with clinical diagnosis of MOE. Clinical query was to assess disease activity and extent. Patients were diagnosed after clinical history and local examination in outpatients department. Mean-age of patients was 60.4years. Mean-dosage of F-18 FDG administered was 7.3mCi (270.1MBq) according to weight-based protocol of 0.08-0.1mCi/kg body-weight (3.0-3.7Mbq/kg-bw). Patients mean blood sugar level was 8.96mmol/l and mean BMI 36.16kg/m2. Patients underwent dedicated head and neck PET/CT protocol 60 minutes post tracer injection followed by vertex to mid-thigh exam. Low-dose CT acquired for anatomical localization and attenuation correction. Study was marked positive if there was an abnormal tracer activity depicting significant disease activity, using maximum Standardized Uptake Value (SUVmax). Local disease extent was also assessed.
6 out of 8 (75%) studies were positive with asymmetric abnormal tracer activity seen (Mean SUVmax 8.15). Two negative studies showed (Mean SUVmax 3.15) with no difference from contralateral side. 4/6 (66.7%) positive studies showed involvement of adjacent bones while in one patient the disease crossed midline and extended to nasopharyngeal region.
F-18 FDG PET/CT imaging has significant clinical utility in management of diabetic patients with MOE depicting disease activity and local extent. Further larger prospective studies are contemplated.
Summary: Evaluation of disease activity and local extent in diabetic patients having malignant otitis externa with F-18 FDG PET/CT imaging.. References: Report abuse »
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