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computed tomography differentiation of primary pulmonary lymphoepithelioma-like carcinoma and small cell lung cancer
EP29112
computed tomography differentiation of primary pulmonary lymphoepithelioma-like carcinoma and small cell lung cancer
Submitted on 02 Nov 2018

Kang-Lung, Lee; Mei-Han, Wu; Chun-Ku, Chen; Ying-Yu, Jhang; Yi-Chun, Chen
Taipei Veterans General Hospital
This poster was presented at BIR Annual Congress 2018
Poster Views: 146
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Poster Abstract
Aims and objectives
To assess computed tomography (CT) characteristics of lymphoepithelioma-like carcinoma (LELC) and differentiate CT features of LELC from small cell lung cancer (SCLC).

Methods and materials
By retrospectively analyzed the lung cancer registration database of our institution, a total of 20 patients proved to have LELC were enrolled. We matched the patients having a diagnosis of SCLC with patients having a diagnosis of LELC by 1:1 in terms of tumor stage. Pretreatment CT images of these 40 patients with LELC or SCLC were reviewed by two radiologists in a consensus manner. Continuous variables and categorical variables were tested by Student’s t-test and Fisher’s exact test, respectively.

Results
There is no statistical difference of tumor border, homogeneity of enhancement, prevalence of presence of obstructive pneumonitis, pleural effusion, lymphangitic spreading, pleural effusion, pericardial effusion, lung-to-lung metastasis, calcification or cavity. However, when compared to the muscle, LELC demonstrated a higher percentage of enhancement as compared to SCLE (23.5% ± 0.3% vs -10.7% ± 0.22%, p < 0.01). The prevalence of background emphysematous change of the lung is lower in the LELC group than the SCLC group (10% vs 50%, p < 0.01).


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