« Back
computed tomography differentiation of primary pulmonary lymphoepithelioma-like carcinoma and small cell lung cancer
computed tomography differentiation of primary pulmonary lymphoepithelioma-like carcinoma and small cell lung cancer
Submitted on 02 Nov 2018

Kang-Lung, Lee; Mei-Han, Wu; Chun-Ku, Chen; Ying-Yu, Jhang; Yi-Chun, Chen
Taipei Veterans General Hospital
This poster was presented at BIR Annual Congress 2018
Poster Views: 146
View poster »
Poster Abstract
Aims and objectives
To assess computed tomography (CT) characteristics of lymphoepithelioma-like carcinoma (LELC) and differentiate CT features of LELC from small cell lung cancer (SCLC).

Methods and materials
By retrospectively analyzed the lung cancer registration database of our institution, a total of 20 patients proved to have LELC were enrolled. We matched the patients having a diagnosis of SCLC with patients having a diagnosis of LELC by 1:1 in terms of tumor stage. Pretreatment CT images of these 40 patients with LELC or SCLC were reviewed by two radiologists in a consensus manner. Continuous variables and categorical variables were tested by Student’s t-test and Fisher’s exact test, respectively.

There is no statistical difference of tumor border, homogeneity of enhancement, prevalence of presence of obstructive pneumonitis, pleural effusion, lymphangitic spreading, pleural effusion, pericardial effusion, lung-to-lung metastasis, calcification or cavity. However, when compared to the muscle, LELC demonstrated a higher percentage of enhancement as compared to SCLE (23.5% ± 0.3% vs -10.7% ± 0.22%, p < 0.01). The prevalence of background emphysematous change of the lung is lower in the LELC group than the SCLC group (10% vs 50%, p < 0.01).

[1] L.R. Begin, J. Eskandari, J. Joncas, L. Panasci, Epstein-Barr virus related lymphoepithelioma-like carcinoma of lung, J Surg Oncol 36(4) (1987) 280-3.
[2] J.C. Iezzoni, M.J. Gaffey, L.M. Weiss, The role of Epstein-Barr virus in lymphoepithelioma-like carcinomas, Am J Clin Pathol 103(3) (1995) 308-15.
[3] A.J. Han, M. Xiong, Y.Y. Gu, S.X. Lin, M. Xiong, Lymphoepithelioma-like carcinoma of the lung with a better prognosis. A clinicopathologic study of 32 cases, Am J Clin Pathol 115(6) (2001) 841-50.
[4] Y. Liang, L. Wang, Y. Zhu, Y. Lin, H. Liu, H. Rao, G. Xu, T. Rong, Primary pulmonary lymphoepithelioma-like carcinoma: fifty-two patients with long-term follow-up, Cancer 118(19) (2012) 4748-58.
[5] J. He, J. Shen, H. Pan, J. Huang, W. Liang, J. He, Pulmonary lymphoepithelioma-like carcinoma: a Surveillance, Epidemiology, and End Results database analysis, J Thorac Dis 7(12) (2015) 2330-8.
[6] L. Lin, T. Lin, B. Zeng, Primary lymphoepithelioma-like carcinoma of the
Report abuse »
Ask the author a question about this poster.
Ask a Question »

Creative Commons

Related Posters

The EurOPDX EDIReX project: towards a European Research Infrastructure on patient-derived cancer models
E. Vinolo 1, J.P. Morris 1, D.G. Alférez 2, J. Arribas 3,4,5, C. Bernadó 3,4,5, A. Bertotti 6, A. Bruna 7, A.T. Byrne 8, C. Caldas 7, R.B. Clarke 2, N. Conte 9, R. Corsi 10, S. Corso 6, M. Crespo 3, A. Dahmani 11, V. Dangles-Marie 11, D. Decaudin 11, Z. Dudová 12, A. Fiori 6, S. Giordano 6, M. Hauptsmann 13, M. Hidalgo 14, C. Isella 6, S. de Jong 15, J. Jonkers 13, A. Křenek 12, O. Krijgsman 13, D. Kouřil 12, J.C. Lacal 14, L. Lanfrancone 16, E. Leucci 17, G.M. Mælandsmo 18, E. Marangoni 11, J. Mason 9, M.Th. Mayrhofer 19, A. Mazzocca 6, T.S. Meehan 9, E. Montaudon 11, F. Nem

Outcomes of prolotherapy for intra-tendinous Achilles tears: A case series
Ben Havard, Otto Chan, Dylan Morrissey, Sarah Morton

CT signs of Internal Hernia after Roux En Y bypass
Dr Farah Aldhaher, Dr Michael Steward, Dr Jane Young

Ultrasound guided neck biopsy in the diagnosis of malignancy – an audit of practice
Dr Nuran Seneviratne, Dr Bikram Bhattacharjee, Miss Duaa Khair

Ionising Radiation (Medical Exposure) Regulations : An audit on the documentation of chest radiographs in intensive care patients
E Elwood, D. Castle, J. Page, J. Astin