Abstract: For controlled release systems using non-biodegradable polymeric materials as carriers, the solubility of the drug in the system is the controlling factor for the release rate. For biodegradable polymers, the release rate is controlled both by the solubility of the drug in the system and by the rate of degradation of the polymeric carrier. Summary: In a matrix diffusion-controlled system, the drug is bound to a polymeric carrier in a dispersed form. References: https://www.formulationbio.com/design-services-for-matrix-diffusion-controlled-systems.html
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