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Diagnostic Performance of Acoustic Radiation Force Impulse (ARFI) Quantitative Elastography in the Assessment of Breast Lesions
EP29114
Poster Title: Diagnostic Performance of Acoustic Radiation Force Impulse (ARFI) Quantitative Elastography in the Assessment of Breast Lesions
Submitted on 11 Sep 2018
Author(s): Lai MSL, Moey HL, Tan PP, Sim SJL, Leong CHL
Affiliations: Singapore General HOspital
This poster was presented at British Institute of Radiology Annual Congress 2018
Poster Views: 497
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Poster Information
Abstract: Purpose

There are several elastographic methods which may potentially help to increase the diagnostic accuracy of ultrasound evaluation of breast lesions. Our study evaluates if shear wave elastography (SWE) using acoustic radiation force impulse (ARFI) imaging can effectively evaluate borderline breast lesions with pathologic correlation as the gold standard.

Materials and Methods
Quantitative elastography using the Virtual Touch Imaging Quantification (VTIQ) application was performed on female patients referred to the radiology department for image-guided biopsy of breast masses. The SWE velocities were obtained for region of interests within the breast mass and at the tissue surrounding the mass. SWE velocities of >4.4m/s measured within the mass (SWV1) and >3.0m/s measured at the tissue surrounding the mass (SWV2) were taken as malignant. The sensitivity and specificity of both categories were compared using the Fisher's exact test.
Results

A total of 50 breast lesions (37 benign, 13 malignant; mean size 14 mm) from 46 patients (mean age 50, years; age range, 29–79 years) were evaluated from Oct 2016 – Jan 2018. Twenty-six percent (13/50) were malignant and 74% were benign. The sensitivity and specificity were 92.3% (12/13) and 75.7% (28/37) respectively for SWV1, and 92.3% (12/13, p=1.0) and 64.9% (24/37, p=0.446) for SWV2.

Conclusion

With this method of quantitative elastography, the elasticity measurements of the lesion and its surrounding tissue helped in breast lesion characterization together with B-mode ultrasound.

Summary:
Diagnostic Performance of Acoustic Radiation Force Impulse (ARFI) Quantitative Elastography in the Assessment of Breast Lesions:

Our study evaluates if shear wave elastography (SWE) using acoustic radiation force impulse (ARFI) imaging can effectively evaluate borderline breast lesions with pathologic correlation as the gold standard.
References: 1. Evaluation of Virtual Touch Tissue Imaging Quantification, a New Shear Wave Velocity Imaging Method, for Breast Lesion Assessment by Ultrasound. Micheal Golatta, at el, Biomed Res Int. 2014; 2014:960262

2. Ultrasound elastography: Principles and techniques. J.-L. Gennisson, T. Deffieux, M. Fink, M. Tanter. Diagnostic and Interventional Imaging, Volume 94, Issue 5, 2013, 487–495

3. Diagnostic Value of Virtual Touch Tissue Quantification for Breast Lesions with Different Size. Minghua Yao Jian Wu, Liling Zou, Guang Xu, Juan Xie, Rong Wu, and Huixiong Xu. BioMed Research International Volume 2014, Article ID 142504.
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