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Effect of Gold Nanosemicubes with and without laser exposure on Oral Squamous Cell Carcinoma cell line
Poster Title: Effect of Gold Nanosemicubes with and without laser exposure on Oral Squamous Cell Carcinoma cell line
Submitted on 22 Feb 2019
Author(s): Sara M. Ali 1, Mohamed H. Elmallahy2, Amira M. Gamal-Eldeen 3 and Seham A. Abdel-Ghani 4
Affiliations: 1. Lecturer of Oral Pathology, Faculty of Dentistry, MSA University. 2. Professor of Oral Pathology, Faculty of Dentistry, Ain Shams University. 3. Professor of Biochemistry, Biochemistry Department, National Research Center, Cairo, Egypt. 4. Lecturer of Oral Pathology, Faculty of Dentistry, Ain Shams University.
This poster was presented at Faculty of Oral and Dental medicine, Cairo university, Egypt
Poster Views: 1,406
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Abstract: Oral squamous cell carcinoma (OSCC) represents the most common neoplasm affecting head and neck with a percentage of 95%. The unsatisfactory five years’ survival rate persists despite constant improvement in conventional treatment modalities. Photothermal properties of gold nanoparticles (GNPs) could be employed as a promising alternative therapeutic modality for cancer. The objective of this study was to evaluate the cytotoxic effect of the prepared PEGylated gold nano-semicubes (GNSCs) on oral squamous carcinoma cell line with and without laser exposure. Summary: In this study we examined the effect of GNSCs with and without laser exposure on oral squamous cell carcinoma cell lines References: 1. Abo-Elfadl M., Gamal-Eldeen A., Elshafey M., Abdalla G., Ali S., Ali M. and Zawrah M.: Photothermal therapeutic effect of PEGylated gold nano-semicubes in chemically-induced skin cancer in mice, Journal of Photochemistry & Photobiology, B: Biology. (2016); 164: 21–29.
2. Baharara J., Ramezani T., Divsalar A., Mousavi M. and Seyedarabi A.: Induction of Apoptosis by Green Synthesized Gold Nanoparticles Through Activation of Caspase-3 and 9 in Human Cervical Cancer Cells, Avicenna Journal of Medical Biotechnology, (2016); 8: 75–83.
3. Bao Z., Liu X., Liu Y., Liu H. and Zhao K.: Near-infrared light-responsive inorganic nanomaterials for photothermal therapy, asian journal of pharmaceutical sciences. (2016); 11: 349–364.
4. Cherukuri P., Glazer E. and Curley S.: Targeted hyperthermia using metal nanoparticles, Adv. Drug Deliv. Rev. (2010); 62:339–345.
5. Ghorbani F., Attaran-Kakhki N. and Sazgarnia A.: The synergistic effect of photodynamic therapy and photothermal thera
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