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Enhanced Variant Detection and Sample Complexity Representation with Collibri Whole-Genome and Stranded RNA Library Prep Kits for High-Throughput Illumina Systems
EP30584
Poster Title: Enhanced Variant Detection and Sample Complexity Representation with Collibri Whole-Genome and Stranded RNA Library Prep Kits for High-Throughput Illumina Systems
Submitted on 13 Sep 2019
Author(s): Zana Kapustina, Aliona Markina, Renata Bruzaite, Karolis Matjosaitis, Giedre Stoskiene, Gediminas Alzbutas, Cris Kinross*, Arunas Leipus, Sigita Cinciute, Arvydas Lubys
Affiliations: Thermo Fisher Scientific
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Abstract: Whole-genome sequencing (WGS) and RNA sequencing (RNA-Seq) data are increasingly being utilized to analyze functional variants and changes in gene expression to understand various diseases and predict disease susceptibility or drug response. Next-generation sequencing costs have significantly decreased over the past 10 years, but library prep failure and achieving clean, high-quality data are still challenges. To address these challenges and obtain greater utility from sequencing data, the Invitrogen™ Collibri™ Library Prep Kits for High-Throughput Illumina™ Systems generate libraries more quickly, with less bias, in order to match the speed and capacity of high-throughput Illumina instruments. Summary: The Collibri Library Prep Kits for High-Throughput Illumina Systems are designed for the speed and capacity of high-throughput Illumina instruments. Visual cues at each step of the process provide greater control over library prep success. Further protocol optimizations allow faster workflows that lead to enhanced detection of genomic variants and more relevant transcriptome data.Report abuse »
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