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Experimental evidence of a xylose--catabolic pathway on the pAO1 megaplasmid of Arthrobacter nicotinovorans
EP20592
Poster Title: Experimental evidence of a xylose--catabolic pathway on the pAO1 megaplasmid of Arthrobacter nicotinovorans
Submitted on 20 Dec 2013
Author(s): Marius Mihasan
Affiliations: Alexandra Ioan Cuza University of Iasi
Poster Views: 1,152
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Poster Information
Abstract: Besides the well-characterized pathway for nicotine degradation (Brandsch, 2006), pAO1 carries a gene cluster of a hypothetical pathway for carbohydrate utilization. This cluster consists of ORFs of a transcriptional regulator, of a sugar ABCtransporter and of several putative dehydrogenases and oxidoreductases. Previously, we established that the pAO1 orf39 gene encodes an aldehyde-dehydrogenase (Mihasan et al., 2008) and orf40 encodes an sugar dehydrogenase. The current work is focused on experimental identification of the catabolic pathway substrate of this latter pathway.Summary: The soil bacterium Arthrobacter nicotinovorans carries the pAO1 catabolic megaplasmid which enables it to grow on nicotine (Igloi and Brandsch, 2003).Report abuse »
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