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Flow Enhancement and Dynamic of Microfluidic Base Biosensor
Flow Enhancement and Dynamic of Microfluidic Base Biosensor
Submitted on 30 Oct 2014

Esmail Abdullah Mohammed Basheer, Hayder A.Abdul Bari
University Malaysia Pahang
Poster Views: 1,882
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Poster Abstract
The development of advance technology for medical and biological diagnostician is significantly increased. Electrochemical biosensors become more desirable since it offered an attractive replacement for the bulky and expensive analytical instruments. The design and fabrication of a novel electrochemical biosensor was achieved base on microfluidic chip. The designed biosensor is consisting of two chips; microfluidic chip which was made of PDMS (Polydimethylsiloxane) and the microchannels was created. The second chip is made of glass, where the three electrodes cell was fabricated. This design offered more flexible testing and multi diagnostician at the same chip. The enhancement of the flow in the biosensor was achieved by varying the channel size as well the electrode size. The diffusion of the electrons from the reaction sits to the electrodes surface is the measure obstacles which limits the biosensor sensitivity. In summary, the suggested design is seems to be the key for more efficient and sensitive biosensor.

[1]. Tavares, M. F., & McGuffin, V. L. (1995). Theoretical model of electroosmotic flow for capillary zone electrophoresis. Analytical Chemistry, 67(20), 3687-3696.
[2]. Beebe, D. J., Mensing, G. A., & Walker, G. M. (2002). Physics and applications of microfluidics in biology. Annual review of biomedical engineering,4(1), 261-286.
[3]. Myszka, D. G. (1999). Improving biosensor analysis. Journal of Molecular Recognition, 12(5), 279-284.
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