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EP20462
Abstract: The advantages of DBS are:
• Only low amount (25 µL) of test material needed
• Minimal sample processing needed
• Sample storage and shipment at ambient temperature possible.
However automation of the DBS workflow is needed to enable a through put that can compete with conventional plasma analysis. This poster details how the SCAP™ DBS System allows fully-automated DBS analysis via LC-MS/MS without need of time-consuming spot punching and manual extraction.
Summary: Dried Blood Spot (DBS) analysis is a very promising alternative to conventional whole blood and plasma analysis used in drug discovery and development or later in therapeutic drug monitoring with well documented advantages.
• Only low amount (25 µL) of test material needed
• Minimal sample processing needed
• Sample storage and shipment at ambient temperature possible.
However automation of the DBS workflow is needed to enable a through put that can compete with conventional plasma analysis. This poster details how the SCAP™ DBS System allows fully-automated DBS analysis via LC-MS/MS without need of time-consuming spot punching and manual extraction.
Summary: Dried Blood Spot (DBS) analysis is a very promising alternative to conventional whole blood and plasma analysis used in drug discovery and development or later in therapeutic drug monitoring with well documented advantages.
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
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