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Gene Mining the Spinal and Dental Phenotypes of the Collaborative Cross
EP29253
Gene Mining the Spinal and Dental Phenotypes of the Collaborative Cross
Submitted on 10 Oct 2018

Samuel Bennett, Eason Guo, Curtise Ng, Grant Morahan, Jennifer Tickner, Jiake Xu
The University of Western Australia, Curtin University of Technology
This poster was presented at Australian and New Zealand Orthodontic Research Society 2018
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Poster Abstract
The Gene Mine is the WA component of The Collaborative Cross (CC): a systems genetics resource, consisting of a purpose-built recombinant inbred panel of >1000 mice from over 80 strains, that have been generated and housed at the Animal Resources Centre, Perth [1, 2].

A central aim of The Gene Mine is to provide a stable, reproducible genetic reference platform for quantitative and qualitative analysis of gene-variants, epistatic mechanisms, and environmental factors resulting in disease [3].

We are screening the Gene Mine CC population for spinal and dentofacial deformities.



1. Threadgill DW and Churchill GA. Genetics, 190: 291-94, 2012.
2. Morahan G, Balmer L, and Monley D. Mamm Genome, 19: 390-93, 2008.
3. The Complex Trait Consortium. Nature Genetics, 36: 1133-1137, 2004.
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