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EP39992
Abstract: test kits of the 1957 H2N2 virus were accidentally spread around the world from the College of
American Pathologists.Estimates of US and worldwide deaths caused by this pandemic varies widely
depending on source; ranging from approximately 69,800[6] to 116,000 in the United States,[8] and
worldwide from 1 million to 4 million, with the World Health Organization (WHO) settling on "about 2
million," with an overall mortality rate of 0.6%.[9] Asian Flu was of the H2N2 subtype (a notation that
refers to the configuration of the hemagglutinin and neuraminidase proteins in the virus) of type A
influenza, and an influenza vaccine was developed in 1957 to contain its outbreak.Summary: In February 1957, a new influenza A (H2N2) virus emerged in East Asia, triggering a pandemic (“Asian
Flu”). This H2N2 virus was composed of three different genes from an H2N2 virus that originated from
an avian influenza A virus, including the H2 hemagglutinin and the N2 neuraminidase genes. Influenza
A virus subtype H2N2 (A/H2N2) is a subtype of Influenza A virus. H2N2 has mutated into various strains
including the "Asian flu" strain (now extinct in the wild), H3N2, and various References: 1.Hilleman, Maurice R. (2002). "Realities and enigmas of human viral influenza:
pathogenesis, epidemiology and control". Vaccine. 20 (25–26):
3068–3087. CiteSeerX 10.1.1.523.7697. doi:10.1016/S0264-410X(02)00254-2. PMID 1216325
8.^ 2."The Influenza H5N1 Report". Pliva.com. April 2, 1998. Archived from the original
on 24 October 2004.^ Alexis Madrigal (April 26, 2010). "1889 Pandemic Didn't Need Planes
to Circle Globe in 4 Months". Wired.
3.Wired Science. Archived from the original on April 29, 2010. Retrieved April
American Pathologists.Estimates of US and worldwide deaths caused by this pandemic varies widely
depending on source; ranging from approximately 69,800[6] to 116,000 in the United States,[8] and
worldwide from 1 million to 4 million, with the World Health Organization (WHO) settling on "about 2
million," with an overall mortality rate of 0.6%.[9] Asian Flu was of the H2N2 subtype (a notation that
refers to the configuration of the hemagglutinin and neuraminidase proteins in the virus) of type A
influenza, and an influenza vaccine was developed in 1957 to contain its outbreak.Summary: In February 1957, a new influenza A (H2N2) virus emerged in East Asia, triggering a pandemic (“Asian
Flu”). This H2N2 virus was composed of three different genes from an H2N2 virus that originated from
an avian influenza A virus, including the H2 hemagglutinin and the N2 neuraminidase genes. Influenza
A virus subtype H2N2 (A/H2N2) is a subtype of Influenza A virus. H2N2 has mutated into various strains
including the "Asian flu" strain (now extinct in the wild), H3N2, and various References: 1.Hilleman, Maurice R. (2002). "Realities and enigmas of human viral influenza:
pathogenesis, epidemiology and control". Vaccine. 20 (25–26):
3068–3087. CiteSeerX 10.1.1.523.7697. doi:10.1016/S0264-410X(02)00254-2. PMID 1216325
8.^ 2."The Influenza H5N1 Report". Pliva.com. April 2, 1998. Archived from the original
on 24 October 2004.^ Alexis Madrigal (April 26, 2010). "1889 Pandemic Didn't Need Planes
to Circle Globe in 4 Months". Wired.
3.Wired Science. Archived from the original on April 29, 2010. Retrieved April
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