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How to explore cancer related mutations using NGS
EP32609
Poster Title: How to explore cancer related mutations using NGS
Submitted on 22 May 2020
Author(s): CD Genomics
Affiliations: CD Genomics
Poster Views: 82
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Abstract: Cancer is primarily caused by genetic alterations, which may be inherited or acquired in somaticcells. These alterations in oncogenes, tumor suppressor genes or DNA repair genes may enable cellsto evade growth inhibition in response to growth-inhibitory signals, leading to the development of a tumor. Further mutations may occur in the progeny of the cancer cell, leading to the developmentof tumor cell invasion and metastasis. The application of NGS provides a high-resolution and globalview of the cancer genome in a high-throughput manner, which has revealed a number of novel cancer-related genes and pathways.
Summary: Cancer is primarily caused by genetic alterations, which may be inherited or acquired in somaticcells. These alterations in oncogenes, tumor suppressor genes or DNA repair genes may enable cellsto evade growth inhibition in response to growth-inhibitory signals, leading to the development of a tumor. References: https://www.cd-genomics.com/Report abuse »
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