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How to explore cancer-related mutations using NGS
EP37605
Poster Title: How to explore cancer-related mutations using NGS
Submitted on 01 Sep 2021
Author(s): CD Genomics
Affiliations: CD Genomics
Poster Views: 49
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Poster Information
Abstract: Cancer is primarily caused by genetic alterations, which may be inherited or acquired in somatic cells. These alterations in oncogenes, tumour suppressor genes or DNA repair genes may enable cells to evade growth inhibition in response to growth-inhibitory signals, leading to the development of a tumour. Further mutations may occur in the progeny of the cancer cell, leading to the development of tumour cell invasion and metastasis. The application of NGS provides a high-resolution and global view of the cancer genome in a high throughput manner, which has revealed a number of novel cancer-related genes and pathways. Summary: Cancer is primarily caused by genetic alterations, which may be inherited or acquired in somatic cells. These alterations in oncogenes, tumour suppressor genes or DNA repair genes may enable cells to evade growth inhibition in response to growth-inhibitory signals, leading to the development of a tumour. Further mutations may occur in the progeny of the cancer cell, leading to the development of tumour cell invasion and metastasis. References: https://www.cd-genomics.com/Whole-Genome-Sequencing.htmlReport abuse »
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