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EP40016
Abstract: The adaptive immune system plays an extremely important role in fighting against pathogens and cancers as well as protecting the body. The basis of the adaptive immune system is fundamentally dependent on the great diversity of T-cell receptors (TCRs) and B-cell receptors (BCRs) that recognize epitopes from a large variety of exogenous antigens and endogenous factors. T cells and B cells are the two major cell populations of the adaptive immune system, which are key measures of immune complexity. Meanwhile, the complementary determining region (CDR) exists in both TCR and BCR, containing CDR1, CDR2, and CDR3, with CDR3 being the most variable and playing a significant role in antigen recognition. The study of the immune repertoire is essential to understanding the immune profile. It ultimately reveals the discovery of new infection factors and potentially aids in the development of antibodies and vaccines, clinical diagnosis, treatment, and prevention. Summary: The study of the immune repertoire is essential to understanding the immune profile. It ultimately reveals the discovery of new infection factors and potentially aids in the development of antibodies and vaccines, clinical diagnosis, treatment, and prevention. References: https://www.cd-genomics.com/immune-repertoire-sequencing.html
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