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Is There an Association Between H. pylori infection and MALT lymphoma development ?!
Poster Title: Is There an Association Between H. pylori infection and MALT lymphoma development ?!
Submitted on 02 Apr 2020
Affiliations: Zagazig University
This poster was presented at (Gastrointestinal Lymphomas Updates),Zagazig University,Egypt
Poster Views: 686
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Abstract: The gastrointestinal tract (GIT) is the most commonly involved site of extranodal lymphomas. The close association between chronic inflammation and specific GIT lymphomas not only provide interesting insights into the pathobiology of lymphomas but also poses unique diagnostic and treatment challenges.Twenty-two patients positive for H. pylori with low-grade gastric B-cell MALT lymphoma were examined by echo- endoscopy at the time of diagnosis. Treatment for H. pylori consisted of a 2-week. Patients were followed up by endoscopy and biopsy.H. pylori was eradicated in all patients. Complete regression of MALT lymphoma was observed in 12 patients , partial regression in 5 patients, and no response in 5 patients during follow-up.There for H.Pylori eradication plays an important role in treatment of MALT lymphoma.Summary: MALT lymphoma and H.Pylori have a close relationship,As H.Pylori infection predispose to MALT lymphoma development.By eradicating H.pylori we can Treat This type of GIT lymphoma.References: 1. Pereira M.-I., Medeiros J.A. Role of Helicobacter pylori in gastric mucosa-associated lymphoid tissue lymphomas. World J. Gastroenterology. 2014;20:684–698.
2. Malfertheiner P., Megraud F., O’Morain C.A., Atherton J., Axon A.T., Bazzoli F., Gensini G.F., Gisbert J.P., Graham D.Y., Rokkas T., et al. Management of Helicobacter pylori infection—The Maastricht IV/ Florence Consensus Report. Gut. 2012;61:646–664.
3. Backert S., Ziska E., Brinkmann V., ZimnyArndt U., Fauconnier A., Jungblut P.R., Naumann M., Meyer T.F. Translocation of the Helicobacter pylori CagA protein in gastric epithelial cells by a type IV secretion apparatus. Cell. Microbiol. 2000;2:155–164.
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