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low-volume workflows improve the quality of drug discovery: two case studies
EP31201
Poster Title: low-volume workflows improve the quality of drug discovery: two case studies
Submitted on 10 Jan 2020
Author(s): Margaret Kenney#, Archi Joardar#, Vasudeo Badarinarayana#, Joby Jenkins*
Affiliations: *SPT Labtech Ltd, Melbourn Science Park, UK, #Icagen, Tucson, AZ, USA
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Poster Information
Abstract: Assay miniaturisation benefits drug discovery workflows by decreasing the amount of samples and reagents that are required. At the same time, low-volume assays reduce costs.

The limiting factor in being able to miniaturise assays is typically the ability to pipette small volumes of various liquids, accurately and reproducibly.

Scientists at Icagen Tucson Innovation Center (Tucson, AZ, USA), a specialised pharmaceutical partnering organisation with a focus on early drug discovery, evaluated the use of SPT Labtech’s mosquito® LV for low-volume qRTPCR and serial dilution of drug compounds. Here we demonstrate that automated liquid handling can successfully improve the quality of these applications in drug discovery.
Summary: SPT Labtech’s mosquito LV was validated for two
different drug discovery applications:

qRTPCR low-volume workflow

Low-volume drug dilution for use in multiple
assays
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