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METASTATIC PLEOMORPHIC RHABDOMYOSARCOMA TO THE MANDIBLE: REPORT OF A RARE CASE
EP31296
Poster Title: METASTATIC PLEOMORPHIC RHABDOMYOSARCOMA TO THE MANDIBLE: REPORT OF A RARE CASE
Submitted on 08 Feb 2020
Author(s): Omneya Ramadan1, Moataz Rizq2 and Mohammad Nawwar2
Affiliations: 1 Ass. Prof. Oral Pathology Department, Faculty of dentistry, Alexandria University. 2 Maxillofacial & Plastic Surgery Department, Faculty of Dentistry, Alexandria University.
This poster was presented at 2nd annual scientific day of the oral and maxillofacial pathology department, Cairo University
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Poster Information
Abstract: Abstract
Pleomorphic rhabdomyosarcoma is a rare and aggressive variant of rhabdomyosarcoma (RMS) that usually occurs only in adults aged 45 years or older. Jaw metastasis from a soft-tissue sarcoma of the extremity is likewise very rare, with only a few previously reported cases. Here, we describe the case of a 47-year-old female patient with mandibular metastasis from a previously excised pleomorphic RMS of the right thigh but died 1 month after due to lung metastases. This is, to our knowledge, the first reported case of mandibular metastasis from pleomorphic rhabdomyosarcoma of the extremity. In cases such as these, patients may have widespread disease, and thus, surgery may only have a limited role in its management. Optimal treatment remains undefined.
Summary: PRMS is a clinically aggressive neoplasm that frequently metastasizes early in its course. As metastatic tumours to maxillofacial region are uncommon, a thorough morphological analyses and careful interpretation of immunohistochemical markers is necessary to arrive at a correct diagnosis.
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