Abstract: The mutation rate of the mitochondrial genome is 10 to 17 times higher than that of nuclear DNA. Although the mtDNA repair system does exist, it is not enough to counteract oxidative damage of the mitochondrial genome and lack of protective histones. Most of the mitochondrial DNA changes are neutral polymorphisms. The first batch of pathogenic mitochondrial DNA mutations was discovered in 1988. Since then, more than 250 pathogenic mtDNA mutations (point mutations and rearrangements) have been characterized, but the prevalence of mtDNA mutations is still underestimated.Summary: Creative Biogene not only provides mtDNA mutation screening, but we can also customize professional mtDNA mutation and disease association analysis services for you according to your project.References: https://www.mitochondriasci.com/disease-association-analysis.html
Ask the author a question about this poster.
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
circRNA Microarray Service
circRNA Sequencing Service
Mitochondrial Comparative Genomics
Genetically Engineered Bacterias Drugs Based on htDNA-chip®