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Myth Busters: The Truth About Metabolomics and High Resolution Gas Chromatography Time-of-Flight Mass Spectrometry
EP23002
Poster Title: Myth Busters: The Truth About Metabolomics and High Resolution Gas Chromatography Time-of-Flight Mass Spectrometry
Submitted on 19 May 2015
Author(s): David E. Alonso, Joe Binkley, and Lorne Fell
Affiliations: LECO Corporation
This poster was presented at ASMS 2014
Poster Views: 2,309
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Poster Information
Abstract: The best approach for comprehensive profiling of metabolites is through a combination of instrumental techniques (e.g., GC-MS, LC-MS, FT-NMR, etc.). GC-MS offers analytical advantages that complement other analytical techniques. The intent of this poster is to dispel the myths about the shortcomings of GC-MS as a technique for metabolomic studies.
Summary: The data summarized in this presentation dispels myths associated with the utilization of GC-MS for analytes which are critical for metabolomic studies. GC-HRT provides high quality, accurate mass data for:
-Spectral similarity searches (NIST, Wiley, etc.)
-Formula determination (fragment, molecular & adduct ions)
-GC-HRT is an indispensible tool for the analysis of complex biological samples.
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