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N-terminal sequencing by Edman degradation or mass spectrometry (MS)
EP32833
Poster Title: N-terminal sequencing by Edman degradation or mass spectrometry (MS)
Submitted on 27 Jul 2020
Author(s): Creative Proteomics
Affiliations: Creative Proteomics
Poster Views: 79
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Poster Information
Abstract: Edman sequencing and MS-based sequencing have their own features. Edman sequencing can accurately analyze N-terminal amino acid sequence, especially discrimination of isoleucine/leucine, and glutamine/lysine. Our protein sequencer system automates the Edman reaction, HPLC separation and detection, and data analysis. For MS-based N-terminal sequencing, we can analyze the N-terminal blockage and post-translational modifications (PTMs) by high-resolution mass spectrometers. And we can use a combination of 2 or 3 different proteases to increase the sequence coverage.Summary: Creative Proteomics can provide N-terminal sequencing by Edman degradation or mass
spectrometry (MS), with complementary advantages to each other. We can provide Nterminal sequence analysis of peptides, therapeutic proteins, monoclonal antibodies, and protein vaccines.
References: https://www.creative-proteomics.com/pdf/proteomics-flyer-n-terminal-sequencing.pdfReport abuse »
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