Abstract: Nanoparticles have a high surface area to volume ratio, which allows them to hold a lot of material on their surface. When used as nanodrug carriers, the delivery of water-insoluble drugs is improved by delivering small particle size drugs that dissolve faster in the blood stream, resulting in targeted drug delivery in a cell- or tissue-specific manner. Carriers used for drug delivery include liposomes, polymers, inorganic nanoparticles and protein-based nanoparticles, etc. Summary: Nanomedicines reach the level of ultra-fine powder, and the specific surface area is significantly increased to improve bioavailability.References: Bipul Kumar, et al. Recent advances in nanoparticle-mediated drug delivery. Journal of Drug Delivery Science and Technology, 2017, 41.
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Simulation of Rituximab and Natalizumab biomarker efficacy using simplified QSP model of B- and T- lymphocyte dynamics in Multiple Sclerosis
Anna Mishina (1,2), Tatiana Karelina (1), Evgeny Metelkin (1), Veronika Musatova (1)
Oral Thin Films Technology
Drug Delivery System Development
NMR Spectrum Prediction
Heta language: Modularity and Reusability in QSP modeling platforms