The 28-year-old female, from Brasília, Brazil, presented in April, 2018 to the Section of Neurology at Brasília Air Force Hospital (HFAB) with no pathological history, came to the complaint with amaurosis on the sudden left that evolved from partial to total in 48 hours and persistent headache. Complaint for more than one year of paraesthesia of the upper limbs without considering that fact to seek medical assistance. After investigation including nuclear magnetic resonance (MRI) of the brain and spinal cord and laboratory findings, the positive test for anti-immunoglobulin G antibodies (AQP4-IgG).
In the cervical MRI, demonstrated T2-hyperintense (Figure-1E) demyelinating areas extending from C2 to C5. The cranial MRI examination describes T2-hyperintense with increased post Gadolinium T1 at the left optic nerve. The patient was diagnosed with NMO according to the diagnostic criteria which were revised in 2006 and 2015, and 1 gr / day IV methylprednisolone was administered for 7 days
Remain in follow-up service.

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