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NGS Methods for Profiling DNA Methylation
EP37816
Poster Title: NGS Methods for Profiling DNA Methylation
Submitted on 02 Nov 2021
Author(s): CD Genomics
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Poster Views: 109
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Poster Information
Abstract: One of the most researched epigenetic alterations is DNA methylation, which is the addition of a methyl group to the fifth carbon of cytosine (C) mediated by DNA methyltransferases (Dnmts), resulting in 5-methylcytosine (5mC). DNA methylation occurs mostly in CpG settings, although it can also be found in non-CpG situations. DNA methylation is heritable and has been linked to a variety of biological activities such as transcriptional repression, transposon inactivation, X chromosome inactivation, embryonic development, genomic imprinting, and chromatin structural changes. Summary: One of the most researched epigenetic alterations is DNA methylation, which is the addition of a methyl group to the fifth carbon of cytosine (C) mediated by DNA methyltransferases (Dnmts), resulting in 5-methylcytosine (5mC). References: https://www.cd-genomics.com/DNA-Methylation-Microarray-Service.htmlReport abuse »
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