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175:Oral Squamous Cell Carcinoma Of Young Adults Less Than 40 Years Of Age[AAOM2020}
EP35989
Poster Title: 175:Oral Squamous Cell Carcinoma Of Young Adults Less Than 40 Years Of Age[AAOM2020}
Submitted on 27 Mar 2021
Author(s): Ayaka Abe, Kenji Kawano
Affiliations: Department of Oral & Maxillofacial Surgery, Oita University, Oita, JAPAN
This poster was presented at 2021 American Academy of Oral Medicine Virtual Conference
Poster Views: 322
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Poster Information
Abstract: Subjects and Methods: Thirty OSCC patients under 40 years of age, who visited our department between 1985 and 2019, were examined. Clinical data were obtained from the patients’ chart. HPV infection was investigated by p16 immunostaining against primary tumors.

Results: Patients consisted of 16 males and 14 females. The primary site was tongue in 26 out of 30 patients (86.7%). T1/T2 were 19 (63.3%) and T3/T4 were 11 (36.7%). Eleven male and 3 female patients were former or current smokers. Next, we divided 30 patients into 2 groups: the 1985~2000 group and the 2001~2019 group. The 1985~2000 group and the 2001~2019 group contained 10 and 20 patients, respectively, showing a twofold increase in the latter. In the both groups, male : female ratio was approximately 1:1, and tongue was the most frequent primary site. T1/T2 patients increased from 50% in the 1985~2000 group to 75% in the 2001~2019 group, indicating a recent tendency of early consultation. On the other hand, patients with smoking habit did not decrease: 40% and 50% in the 1985~2000 and the 2001~2019 groups, respectively. HPV infection was demonstrated in only 3 out of 30 patients (10%).

Conclusions: 1) OSCC of young adults showed a higher percentage of tongue as the primary site than OSCC of all ages (generally 40-50%). 2) It was not suggested that HPV infection be a causative factor of oral carcinogenesis in the present series of young adult OSCC.
Summary: Objective: This study aimed to characterize clinical aspects of oral squamous cell carcinoma (OSCC) of young adults in Oita, Japan.

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