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Phage Display Technology
Poster Title: Phage Display Technology
Submitted on 20 Apr 2020
Author(s): Creative Biolabs
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Poster Information
Abstract: Creative Biolabs is a leading service provider of phage display library construction and screening. In a phage display library, a variety of peptides, small antibodies [e.g. scFv and Fab] or proteins are displayed on the surface of filamentous phage [M13, fd, and f1 strains] as fusion proteins with one of the coat proteins of the phage virions, while the genetic materials encoding the peptides/proteins are housed within the virions. Using a binding-based process called biopanning, a small number of phages that display proteins/peptides specifically binding to a target of interest can be rescued from a phage library that usually displays a repertoire of many billions of unique peptides/proteins. Finally, the peptides/proteins displayed by the selected phages can be identified by phage amplification and DNA sequencingSummary: Creative Biolabs offers high-quality phage display library construction and custom phage display library screening services for a broad range of project objectives including but not limited to:
Function peptide discovery
Therapeutic antibody discovery
Monoclonal antibody discovery from a variety of species includes: human, monkey, llama,
camel, shark, alligator, mouse, rat, hamster, guinea pig, rabbit, chicken, dog, bovine, goat,
sheep, and ferret.
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