Posters
« Back
Phenylephrine Effects on Cerebral Ischemia
EP27451
Phenylephrine Effects on Cerebral Ischemia
Submitted on 16 Apr 2018

James Crunkilton
Nova Southeastern University
This poster was presented at AAAA
Poster Views: 306
View poster »
Poster Abstract
Perioperative ischemia is an area of ongoing concern for anesthesia providers. The issue is multifactorial and individual patient risk factors influence both outcomes and approach to care. Intraoperative hypotension is an independent risk factor for ischemic stroke. Response to adrenergic stimulation of the cerebral vasculature is not fully understood. There is controversy on the usefulness of phenylephrine in its influence on cerebral blood flow, cerebral blood volume, and cerebral tissue oxygenation. This study aims to describe the effects of phenylephrine on cerebral oxygenation, identify physiologic factors that influence the efficacy of phenylephrine in preventing cerebral ischemia, and determine the actual effectiveness of phenylephrine at prevention of cerebral ischemia.


Sperna Weiland, N. H., Brevoord, D., Jöbsis, D. A., Beaumont, E. M. F. H., Evers, V., Preckel, B., ... & Immink, R. V. (2017). Cerebral oxygenation during changes in vascular resistance and flow in patients on cardiopulmonary bypass–a physiological proof of concept study. Anaesthesia, 72(1), 49-56.

McDonnell, N. J., Paech, M. J., Muchatuta, N. A., Hillyard, S., & Nathan, E. A. (2017). A randomised double‐blind trial of phenylephrine and metaraminol infusions for prevention of hypotension during spinal and combined spinal–epidural anaesthesia for elective caesarean section. Anaesthesia, 72(5), 609-617.

Ogoh, S., Sato, K., Fisher, J. P., Seifert, T., Overgaard, M., & Secher, N. H. (2011). The effect of phenylephrine on arterial and venous cerebral blood flow in healthy subjects. Clinical physiology and functional imaging, 31(6), 445-451.

Ogoh, S., Sato, K., Okazaki, K., Miyamoto, T., Secher, F., Sørensen, H., ... & Secher, N. H. (2014). A decrease in spatially
Report abuse »
Questions
Ask the author a question about this poster.
Ask a Question »

Creative Commons

Related Posters


A Novel Method For Discovery of Peripheral Blood Biomarkers in Idiopathic Pulmonary Fibrosis Using Extensive Depletion and TMTcalibratorTM Tissue-Enhanced Plasma Proteomics
I. Pike1, M. Bremang1, P.J. Wolters 2, R. Gaster3, S. Turner3, M. Decaris3

COMBINED HYSTEROLAPAROSCOPY IN EVALUATION OF FEMALE INFERTILITY
Nikita Gandotra

Things just keep changing: Family caregivers' perceptions of the impact of Huntington's disease on caregiver burden
Jess Kaplonyi, Dr Christopher Lind, Catherine Christian, Irene Scott

The EurOPDX EDIReX project: towards a European Research Infrastructure on patient-derived cancer models
E. Vinolo 1, J.P. Morris 1, D.G. Alférez 2, J. Arribas 3,4,5, C. Bernadó 3,4,5, A. Bertotti 6, A. Bruna 7, A.T. Byrne 8, C. Caldas 7, R.B. Clarke 2, N. Conte 9, R. Corsi 10, S. Corso 6, M. Crespo 3, A. Dahmani 11, V. Dangles-Marie 11, D. Decaudin 11, Z. Dudová 12, A. Fiori 6, S. Giordano 6, M. Hauptsmann 13, M. Hidalgo 14, C. Isella 6, S. de Jong 15, J. Jonkers 13, A. Křenek 12, O. Krijgsman 13, D. Kouřil 12, J.C. Lacal 14, L. Lanfrancone 16, E. Leucci 17, G.M. Mælandsmo 18, E. Marangoni 11, J. Mason 9, M.Th. Mayrhofer 19, A. Mazzocca 6, T.S. Meehan 9, E. Montaudon 11, F. Nem

Outcomes of prolotherapy for intra-tendinous Achilles tears: A case series
Ben Havard, Otto Chan, Dylan Morrissey, Sarah Morton