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Preparation of Photonic Biosensors by Inkjet Printing Technology
EP24619
Poster Title: Preparation of Photonic Biosensors by Inkjet Printing Technology
Submitted on 28 Oct 2016
Author(s): F. Strassera, c, E. Melnika, R. Heera, P. Muellnera, G. Mutinatia, R. Hainbergera , J. Kraftb, G. Meinhardtb, J. Siegertb, P. Lieberzeitc
Affiliations: a AIT Austrian Institute of Technology GmbH, Health & Environment Department, Molecular Diagnostics, Vienna, Austria b ams AG, Unterpremstätten, Austria c University of Vienna, Institute of Physical Chemistry, Vienna, Austria
This poster was presented at Biodetection & Biosensors
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Poster Information
Abstract: In order to enable local functionalization of label-free optical waveguide biosensors in a cost effective mass-fabrication compatible manner, we investigate surface modification employing inkjet printing of a) functional polymers (biotin-modified polyethylenimine (PEIB)) to implement high receptor densities at the surface and b) UV-curable benzophenone dextran (benzo-dextran) to form a voluminous porous hydrogel matrix. The combination of these approaches on a single chip is promising for the detection of biomolecules. We evaluate these functional polymers and hydrogels on an integrated four-channel silicon nitride (Si3N4) waveguide based Mach-Zehnder interferometric (MZI) sensor platform operating at a wavelength of 850nm (TM-mode).Summary: In order to enable local functionalization of label-free optical waveguide biosensors in a cost effective mass-fabrication compatible manner, we investigate surface modification employing inkjet printing of functional polymers and UV-curable benzophenone dextran.References: [1] K. Tiefenthaler, W. Lukosz, J. Opt. Soc. Am. B 6:209–220 (1989).
References [2] E. Melnik, P. Muellner, O. Bethge, E. Bertagnolli, R. Hainberger, M. Laemmerhofer, Chem. Commun. 50:2424 (2014).
[3] A. Brunsen, U. Ritz, A. Mateescu, I. Hoefer, P. Frank, B. Menges, A. Hofmann, P.M. Rommens, W. Knoll, U. Jonas, J.
Mater. Chem. 22 (2012) 19590.
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