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Rapid Review on Novel Corona Virus
EP39407
Poster Title: Rapid Review on Novel Corona Virus
Submitted on 15 Oct 2022
Author(s): Saurav Suryavanshi
Affiliations: Mahatma Gandhi College of Pharmaceutical Sciences Jaipur
Poster Views: 191
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Poster Information
Abstract: Novel coronavirus also known as severe acute respiratory syndrome Coronavirus 2 (SARS-
CoV-2) was emerged from Wuhan, China and has since spread catastrophically over the
world.
India, a country with a large population, is also impacted by this deadly infection. Bats were
considered as its main host, but in human the COVID-19 disease spread from person to
person via droplet nuclei. Depending on the immune condition of the patients, the disease's
main symptoms include atypical pneumonia, fever, breathing difficulties, a reduction in
SPO2, and finally death from respiratory failure. The incubation period can last up to 14
days.
Coronaviruses are positive-sense, single-stranded RNA viruses and have a genome (30 kb)
that contains two terminal untranslated sections and twelve putatively functional open
reading frames (ORFs) that are thought to code for both structural and non-structural
proteins.
Four structural proteins—spike protein (S), envelope (E), membrane (M), and
nucleocapsid—and sixteen potential non-structural proteins—including proteases, RNA-
dependent RNA polymerase, helicase, and other proteins involved in the transcription and
replication of SARS-CoV-2, With a high viral load in the body, SARS-CoV-2 infection
damage human lungs through cytokine storm, especially in older people and those with
immunosuppressive diseases. Although many medications have been modified and used,
but till now, no specific antiviral medicine has been approved by the FDA to treat COVID -
19.
This review article provides a current status and information of the COVID-19, Pandemic,
an overview of evolutionary history, different variants, diagnosis, and available treatment
methods, vaccinations and Preventive majors.
Summary: In 1965, researchers found the first human Corona virus. Scientist found a various but
similar human and animal viruses and named them due to their appearance as Crown-like.
Corona viruses are a big family, called as Coronaviridae.
Corona viruses are enveloped, positive-sense RNA viruses with a nucleocapsid of helical
symmetry having diameter of 60–140nm. characterized by club-like spike projections of
protein on the surface, with a crown-like (Latin for crown is ‘coronam
References: 1. Andrews MA, Areekal B, Rajesh KR, Krishnan J, Suryakala R, Krishnan B, Muraly CP,
Santhosh PV. First confirmed case of COVID-19 infection in India: A case report. The
Indian journal of medical research. 2020 May;151(5):490.
2. Belfin RV, Bródka P, Radhakrishnan BL, Rejula V. COVID-19 peak estimation and effect
of nationwide lockdown in India. MedRxiv. 2020 Jan 1.
3. Ananthalakshmi V. The current situation of COVID-19 in India. Brain, Behavior, and
Immunity-Health. 2021 Feb 1;11:100200.
4. Gettleman J, Schultz K. Modi orders 3-week total lockdown for all 1.3 billion Indians. The
New York Times. 2020 Mar 24;24:0362-433.
5. Jeffrey G, Kai S. Modi orders 3-week total lockdown for all 1.3 billion Indians. New York
Times Company. 2020 Mar.
6. https://timesofindia.indiatimes.com/life-style/health-fitness/health-news/coronavirus-amid-
rising-omicron-cases-here-are-the-drugs-and-treatments-available-for-covid-19-
patients/photostory/8
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