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Short Communication: Natural Inhibitors of Wnt Signaling Pathway
Poster Title: Short Communication: Natural Inhibitors of Wnt Signaling Pathway
Submitted on 07 Feb 2018
Author(s): Souvik Mukherjee & Deepronil Roy
Affiliations: Central University of Punjab, Bathinda, Punjab-151001
Poster Views: 380
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Poster Information
Abstract: The Wnt signalling pathway, an evolutionarily conserved one, is essential in many biological processes. The Wnt signal is associated with several diseases, particularly cancer and neurodegenerative diseases. Recently, high-throughput
screening systems have been developed to rapidly identify compounds, including natural compounds,
that target the Wnt signal. Some studies on natural inhibitors of the Wnt signal have also suggested
their possible target.
Summary: In this poster, we tried to depict the future therapeutic uses of naturally derived chemical compounds that can regulate one of the most important cell communication pathways, i.e., Wnt signaling pathway. References: 1. N. Inestrosa, C. Montecinos-Oliva and M. Fuenzalida, J. Neuroimmune Pharmacol., 2012, 7, 788–807.
2. V. Stambolic, L. Ruel and J. R. Woodgett, Curr. Biol., 1996, 6,1664–1669.
3. H. Choi, J. Gwak, M. Cho, M.-J. Ryu, J.-H. Lee, S. K. Kim, Y. H. Kim, G. W. Lee, M.-Y. Yun, N. M. Cuong, J.-G. Shin, G.-Y. Song and S. Oh, Biochem. Biophys. Res. Commun.,2010, 391, 915–920.

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