« Back
Squamous cell carcinoma in an ovarian dermoid cyst - a case report
Poster Title: Squamous cell carcinoma in an ovarian dermoid cyst - a case report
Submitted on 25 Sep 2019
Author(s): Victoria Crowe, Yinghui Wu
Affiliations: Department of Clinical Radiology, Cambridge University Hospitals NHS Foundation Trust
This poster was presented at BIR Annual Congress 2019
Poster Views: 55
View poster »

Poster Information
Abstract: An ovarian dermoid cyst, also known as a mature cystic teratoma, is the most common ovarian germ cell tumour and accounts for 10-20% of all ovarian tumours.[1] A rare complication, developing in 1-2% of cases, is malignant degeneration.[2] The annual incidence of malignant degeneration is reported to be in the range of 1.2-14.2 cases per 100,000 people.[3] The most common histological diagnosis in such cases is squamous cell carcinoma, representing transformation of ectodermal tissue elements[3].
We present the case of a 49-year-old female with a complex abdominopelvic mass, found to be a keratinising squamous cell carcinoma within an ovarian dermoid cyst. We discuss the imaging features of dermoid cysts and those concerning for malignancy, highlighting the heterogenous appearances of ovarian dermoids and the need for a high index of clinical suspicion, in order to detect malignancy.
This case study illustrates some of the imaging features associated with ovarian dermoid cysts, including radiological features that should raise concern about malignancy. Malignant degeneration within a dermoid cyst is a rare complication that can be easily missed, mandating awareness of the radiological signs and a high index of suspicion. 
[1] Berek JS and Hacker NF. Practical Gynecologic Oncology. 4th ed. Philadelphia: Lippincott Williams & Wilkins; 2005. 
[2] Avci S, Selcukbiricik F, Bilici A, et al. Squamous Cell Carcinoma Arising in a Mature Cystic Teratoma. Case Reports in Obstetrics and Gynaecology. 2012;2012:314535.
[3] Hackethal A, Brueggmann D, Bohlmann MK, et al. Squamous-cell carcinoma in mature cystic teratoma of the ovary: systematic review and analysis of published data. Lancet Oncol. 2008 Dec; 9(12):1173–80.
[4] Timmerman D, Testa AC, Bourne T, et al. Simple ultrasound-based rules for the diagnosis of ovarian cancer. Ultrasound Obstet Gynecol. 2008 Jun; 31(6): 681-90.
[5] Foti PV, Attina G, Spadola S, et al. MR imaging of ovarian masses: classification and differential diagnosis. Insights Imaging. 2016 Feb; 7(1): 21-41.
[6] Hubert J. and Bergin D. Imaging the female pelvis: When should MRI be considered? Applied Radiology. 2011. Oct. [ONLINE]. .
[7] Dhanda S, Thankur M, Ke
Report abuse »
Ask the author a question about this poster.
Ask a Question »

Creative Commons

Related Posters

Etiological diagnostics of cardiomyopathies in the cardiology unit of the HUEH internal medicine department during the period from 8 January 2014 to 14 June 2014
*Axler JEAN PAUL; **Lesly Ed. ARCHER; *Raema Mimrod JEAN; *Gerald VERNELUS; *Rodolph MALEBRANCHE

Medical Student: Move over Stem Cells – Exosomes are Here! What are Exosomes & their role in Regenerative Medicine?
Amartej Singh Deol MD4 & Advisor: Shivinder S. Deol MD

Briand Bounkeu MD; Ravi Shekarappa MD; La Toya Jackson DO, FAAFP; Chinedu Ivonye MD, FACP; Cristal Kudiwu MD

Striving for Equity in Surgical, Anesthesia, and Obstetric Research in Haiti: A Multi-Partner, International Research Training Collaboration
Dr. Jean Alouidor*, Dr. Frédéric Barau Déjean*, Dr. Louis-Franck Télémaque, Dr. Ronald Eveillard, Dr. Laëlle Mangurat, Dr. Isaac Martineau, Dr. Chartelin Jean Isaac, Dr. Darlène Rochelin Paultre, Carine Réveil Jean-Baptiste, Dr. Lucile Louis Riché, Dr. Jordan Pyda, Rolvix Patterson III, Dr. Blake Alkire, Dr. Eunice Dérivois-Mérisier (*Co-First Authors)

Projektstatus: Entwicklung einer konsensbasierten Therapieempfehlung für die PADOVAN-METHODE® in der Neurorehabilitation
Eisenmeier, Dimitri1; Ostermann, Thomas1; Vogel, Hannah1; Fetz, Katharina1