Posters
« Back
The P450-Glo™ CYP2B6 Assay: a Rapid and Selective Assay for Measuring CYP2B6 Induction and Inhibition
EP23517
Poster Title: The P450-Glo™ CYP2B6 Assay: a Rapid and Selective Assay for Measuring CYP2B6 Induction and Inhibition
Submitted on 09 Oct 2015
Author(s): Dongping Ma, Hui Wang, Poncho Meisenheimer, James J. Cali
Affiliations: Promega Corporation
Poster Views: 1,364
View poster »


Poster Information
Abstract: We have developed a luminogenic CYP2B6 assay for biochemical CYP2B6 inhibition and for cell-based CYP2B6 induction studies. Here we present the CYP2B6 luminogenic assay characterization and demonstrate its utility for measuring time dependent CYP2B6 inhibition, and for measuring CYP2B6 induction in cultured primary human hepatocytes with normalization to viable cell count.Summary: We have developed a luminogenic CYP2B6 assay for biochemical CYP2B6 inhibition and for cell-based CYP2B6 induction studies. Here we present the CYP2B6 luminogenic assay characterization and demonstrate its utility for measuring time dependent CYP2B6 inhibition, and for measuring CYP2B6 induction in cultured primary human hepatocytes with normalization to viable cell count.References: Dongping Ma1, Hui Wang 2, Poncho Meisenheimer 2, James J. Cali1
1R & D, Promega Corporation, Madison, WI 53711; 2R & D, Promega Biosciences, San Luis Obispo, CA 93401
Report abuse »
Questions
Ask the author a question about this poster.
Ask a Question »

Creative Commons

Related Posters


Diagnostic outcomes of MRE as an investigation for NSS of small bowel disease: Can CTE be a cost-effective alternative in patients above 50 years old?
K ElGendy, E Musgrave, M Twemlow

An audit on compliance with the Ottawa Knee Rule in patients with traumatic knee pain
Qasim Afzaal, Saad SIddiqui, Amit Shah

Bleeding Pseudoaneurysm in uncommon locations: interesting cases from St. Peter's Hospital
Dr Joel James (SHO) Dr Chandni Patel (SpR) & Dr Shirish Prabhudesai (Consultant)

Estimating the Mass of the Milky Way Galaxy
Celeste Artiga, Yilun Ma, Ayla Weitz, Alex Ye (Mentor)

An Analysis on the Distribution of the Hubble Parameter across the Sky
Stephanie Bie, Arnav Gulati, Jwalin Joshi, Richard Yu, & Xuyang Yu / Mentors: Yukei Murakami & Andrew Hoffman