Latest ADME Tox Posters
Comparison of hepatocytes in monolayer and RAFT™ 3D Cell Culture System Therese Willstaedt, Maureen Bunger, Lubna Hussain, and Theresa D’Souza
Lonzamore » Unique Users-Initiated Biotransformation Reactions for Analysis of Xenobiotic MetabolismRichard Lee, Rytis Kubilius, Vitaly Lashin, Alexandr Sakharov, Anne Marie Smith
Advanced Chemistry Development, Inc. (ACD/Labs); 8 King Street East, Suite 107; Toronto, ON, Canada; M5C 1B5more » New BIONET Compounds for CNS DiseasesSteve Brough1, Andrew Lowerson1 and Nikolay T. Tzvetkov2
1. Key Organics Ltd, Highfield Road Industrial Estate, Camelford, Cornwall, PL32 9RA, UK 2. NTZ Lab Ltd., Krasno selo 198, 1618 Sofia, Bulgariamore » High-throughput Carbonic Anhydrase Activity and Inhibitor Screening AssaysSuratna Hazra, Ph.D., Grigoriy Tchaga, Ph.D., and Gordon Yan, Ph.D.
BioVision Incmore » A High-Throughput Assay to Measure Phosphoenolpyruvate Carboxykinase (PEPCK) Activity in Biological SamplesShunan Li, Ph.D., Keith Cheung, Ph.D. Grigoriy Tchaga, Ph.D. Jianping Xu, Ph.D. and Gordon Yan, Ph.D. Acknowledments: Kyle Schmitt, Ph.D • Tanvi Gangakhedkar • Gustavo Chavarria, Ph.D. • Kwang Kim, Ph.D. • Robert Stephenson, Ph.D. • Hong Qu, Ph.D.
BioVision, Inc.more » Ganirelix interaction with gonadotropin alpha: in silico insights towards drug-target interactions and implications for assisted reproduction in buffaloesA. Bhardwaj , Varij Nayan
ICAR-National Research Centre on Equines, Hisar-125001, Haryana, India; ICAR-Central Institute for Research on Buffaloes, Hisar-125001, Haryana, Indiamore » Micropatterned polymer scaffolds for guiding 3-dimensional cultivation of cellsJustyna Borowiec, Frank Weise, Jörg Hampl, Patrick Mai, Sukhdeep Singh, Martin Bača, Andreas Schober
Ilmenau University of Technology, Institute of Chemistry and Biotechnology, Department of Nano-Biosystem Technologymore » MatriGrid® - Mimicking real organ structures with biolithomorphic processed porous membranesMai, P.*, Baca, M.*, Borowiec, J.*, Brauer, D.*, Gebinoga, M.*, Hampl, J.*, Schlingloff, G.*, Singh, S.*, Weise, F.*, Behr, R.', Beck, J.", Frey, J.", Voigt, A.", Schober, A.*
* Department of Nano-Biosystem Technology, Ilmenau University of Technology (Germany), ' Degenerative Diseases, German Primate Center, Göttingen (Germany), " Department of Paediatric Haematology and Oncology, Jena University Hospital (Germany)more » Modular air-liquid-interface exposure system (MALIES) for even distribution of aerosolized nanoparticles to membrane culturesMai, P., Hampl, J., Weise, F., Brauer, D., Singh. S., Schober, A.
Department of Nano-biosystem Technology, University of Technology Ilmenau, Germanymore » IntelliXtract 2.0: Simplified Intelligent Component Extraction and DetectionAnne Marie Smith, Richard Lee, Vitaly Lashin, Andrey Paramonov
ACD/Labsmore » A new biotransformation prediction engine integrated into a metabolite identification solution. Richard Lee, Rytis Kubilius, Vitaly Lashin, Alexandre Sakarov
ACD/Labsmore » A new method for analyzing MSe/All Ions Fragmentation in xenobiotic metabolism studiesRichard Lee, Vitaly Lashin, Alexandre Sakarov, Andrey Paramonov
ACD/Labsmore » Priming stategy with sub-50 nanometer capsules and RNAi cargo (“GS-10”) to enhance RNAi and immunotherapy responsesLucas P. Nacusi, Vicci L. Korman, Alex J. Pretti, Diane L. Tobolt, Alvaro Mendoza, Gretchen M. Unger
GeneSegues Therapeutics, Minnetonka, MN 55343more » Passive topical administration of nucleic acids to targeted skin cells via sub-50 nm capsulesG Unger1, V Korman1, D Tobolt1, M Fuentes de Abin2, R Kaspar3, B Kren2, J Ballantyne4, M Murtaugh2
1GeneSegues, Inc., Chaska, MN; 2University of Minnesota, Mpls., MN; 3Transderm, Inc., Santa Cruz, CA; 4Aldevron, Fargo, NDmore » Subcutaneous Delivery of Diagnostics and RNAi to Primary and Metastatic Tumors via Actively-targeted sub-50 nm (s50) CapsulesVicci L. Korman1, Lucas Nacusi1, Alex J. Pretti1, Diane L. Tobolt1, J. David Robertson2, Gretchen M. Unger1
1GeneSegues Therapeutics, Eden Prairie, MN 55347; 2University of Missouri, Columbia, MO 65211 more » Human iPSC-derived cardiomyocytes: A translational model to predict drug-induced cardiac arrhythmias and long-term toxicityR Kettenhofen1, G Luerman1, R Bucerius1, I Kopljar2, DJ Gallacher2, A De Bondt2, E Vlaminckx2, I Van Den Wyngaert2, HR Lu2, H Bohlen1
1 Axiogenesis AG, Cologne, Germany; 2 Discovery Sciences, Janssen Research and Development, Janssen Pharmaceutica, Beerse, Belgium Conference Contact: roman.bucerius@axiogenesis.commore » Electrophysiological and cardiotoxicological characterization of human iPSC-derived cardiomyocytes (hiPSC-CMs) in 3D microtissues and 2D monolayersHortigon-Vinagre, Maria P. 1,2 ; Zamora, Victor1,2 ; Mamta Chabria3 ; Liudmila Polonchuk3 ; Bucerius, Roman4; Burton, Francis. L.1,2 ; Smith, Godfrey L.1,2
1. Clyde Biosciences, Ltd., Biocity Scotland, Bo’Ness Rd., ML1 5UH Newhouse (UK) 2. Institute of Cardiovascular and Medical Sciences, University of Glasgow, G12 8QQ, Glasgow (UK) 3. Pharmaceutical Sciences, Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, CH-4070, Basel, Switzerland 4. Axiogenesis AG, Cologne, Germanymore » Multiwell optogenetics for enhanced control of human iPSC-derived cellsIP Clements, DC Millard, AM Nicolini, CA Arrowood, SA Chvatal, M Clements, JD Ross
Axion BioSystemsmore » CiPA Phase 2 Study: validation of an automated microelectrode array (MEA) assay of hiPSC-derived cardiomyocyte electrophysiology for cardiac safety evaluationDC Millard, AM Nicolini, SA Chvatal, HB Hayes, M Clements, JD Ross
Axion BioSystemsmore » THE REASON BEHIND THE OPTIMAL FAILURE OF MEDICATION IN ICU AT THE END STAGE OF CHFP. Mukesh raja, K. Rose mary, Sk. Rihana parveen, K. Venkata ramana
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