Bruker Daltonics Scientific Posters


Innovations such as Trapped Ion Mobility (TIMS), smartbeam and scanning lasers for MALDI-MS Imaging that deliver true pixel fidelity, and eXtreme Resolution FTMS (XR) technology capable to reveal Isotopic Fine Structure (IFS) signatures are pushing scientific exploration to new heights. Our mass spectrometry solutions enable scientists to make breakthrough discoveries and gain deeper insights.

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Bruker Daltonics Scientific Posters Posters
Real-time search of Ubiquitin diGLY modified peptides and PaSER acquisition control on the timsTOF PRO
Real-time search of Ubiquitin diGLY modified peptides and PaSER acquisition control on the timsTOF PRO
Christopher Adams1; Robin Park1; Nagarjuna Nagaraj4; Sven Brehmer4; Matt Willetts3; Elizabeth Gordon3; Barry M. Zee2; Hayley Peckham2; Kimberly Lee2; Tharan Srikumar3
1Bruker,San Jose,CA;2Cell Signaling Technologies, Danvers, MA;3Bruker, Billerica, MA; 4Bruker, Bremen, Germany

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Proteomic profiling of IDH mutant gliomas enables prediction of chromosomal copy number variations
Proteomic profiling of IDH mutant gliomas enables prediction of chromosomal copy number variations
Marius Felix 1 2 Dennis Friedel 1 2 Ashok Kumar Jayavelu 4 Uwe Warnken 3 Damian Stichel 1 2 Christel Herold Mende 5 Laura Heikaus 6 Andreas von Deimling 1 2 and David E Reuss 1 2
1 Department of Neuropathology, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany 2 Clinical Cooperation Unit Neuropathology, German Cancer Research Center ( German Consortium for Translational Cancer Research ( Heidelberg, Germany 4 Max Planck Institute of Biochemistry, Martinsried Germany 5 Clinical Cooperation Unit Neurooncology German Cancer Consortium, German Cancer Research Center, Heidelberg, Germany 5 Department of Neurosurgery, University Hospital Heidelberg, Heidelberg, Germany 6 Bruker Daltonik GmbH, Bremen, Germany

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OpenTIMS TimsPy TimsR: Open Access to timsTOF Pro Raw Data
OpenTIMS TimsPy TimsR: Open Access to timsTOF Pro Raw Data
Mateusz K. Łącki1, Michał P.Startek2, Sven Brehmer3, Christina Bell3, Ute Distler1, Stefan Tenzer1
1University Medical Center of the Johannes Gutenberg University Mainz, 2Institute of Informatics, University of Warsaw, 3Bruker Daltonik GmbH

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Novel bifunctional material coupled to PASEF enables sensitive extracellular vesicles phosphoproteomic analysis of urine
Novel bifunctional material coupled to PASEF enables sensitive extracellular vesicles phosphoproteomic analysis of urine
Jie Sun1,2, W.Andy Tao3, Xiaoxian Du4 and Xianming Liu4
1Southeast University, Nanjing, Jiangsu Province, China 2Bell Mountain Molecular Medicine, Nanjing, Jiangsu Province, China 3Purdue University, Indiana, United States 4Bruker Daltonics, Shanghai, China SouthMethods UniversitMethodsMethods NanjinMethods ProvinMethods ChinaMethods Methods Methods MediciMethods ProvinMethods ChinaMethods UniversityMethods Methods Methods Methods MethodsMethods Methods ChinaMethods

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Implementation of Holistic Glycopeptide PASEF-DDA Data In Diagnostics
Implementation of Holistic Glycopeptide PASEF-DDA Data In Diagnostics
Hans JCT Wessels1, Purva Kulkarni1, Fokje Zijlstra1, Merel Post1, Melissa Bärenfänger1, Pierre-Olivier Schmit2, Alain J van Gool1, Dirk J Lefeber1
1Translational Metabolic Laboratory, Department of Laboratory Medicine, Radboud university medical center, Nijmegen, the Netherlands; 2 Bruker Daltonique S.A., Wissembourg, France

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Immune suppression in the early stage of COVID 19 disease
Immune suppression in the early stage of COVID 19 disease
Nan Zhang 1 , Siyuan Wang 1 ,Catherine CL Wong 1*,
Center for Precision Medicine Multi Omics Research, Peking University Health Science Center, Peking University, Beijing 100191, China.

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Evaluation of prmPASEF for multiplexed targeted proteomics.
Evaluation of prmPASEF for multiplexed targeted proteomics.
Antoine Lesur1, Jens Decker2, Sven Brehmer2, Pierre-Olivier Schmit3, François Bernardin1, Elisabeth Letellier5, and Gunnar Dittmar1
1Luxembourg Institute of Health, Strassen, Luxembourg, 2Bruker Daltonik GmbH, Bremen, Germany 3Bruker Daltonics S.A., Wissembourg, France 5Department of Life Sciences and Medecine, University of Luxembourg, Luxembourg

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Draft Quantitative Proteomic Atlas of Human Body and Common Carcinomas
Draft Quantitative Proteomic Atlas of Human Body and Common Carcinomas
Liang Yue 1,2,3, Meng Luo 4, Wenhao Jiang 1,2,3, Ning Fan 4, Xiaolu Zhan 6, Fangfei Zhang 1,2,3, Rui Sun 1,2,3, Sainan Li 1,2,3, Tian Lu 1,2,3, Fengchao Yu 7, Guoci Teo ⁷, Alexey I Nesvizhskii ⁷,8, Ben Collins ⁹, Ruedi Aebersold 10,11, Fei Xu 4, Tong Liu ⁶, Yan Li ⁵, Tiannan Guo 1,2,3
1, Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China. 2, Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang, China 3, Institute of Basic Medical Sciences, Westlake Institute for Advanced Study, Hangzhou, Zhejiang, China 4, Department of Anatomy, College of Basic Medical Sciences, Dalian Medical University, No.9 West Section Lvshun South Road, Dalian116044, Liaoning Province, China 5, Department of Anatomy and Physiology, College of Basic Medical Sciences, Shanghai Jiao Tong University, No.280 Chongqing South Road, Shanghai, 200025, China 6, Harbin Medical University Cancer Hospital, 150 Haping Road, Harbin 150081, Heilongjiang Province, China 7, Department of Pathology, University of Michigan, Ann Arbor, Michigan, USA. 8, Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA. 9. Queen's University Belfast, Belfast, Northern Ireland,

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PimMDN: Peptide Ion Mobility Mixture Density Network
PimMDN: Peptide Ion Mobility Mixture Density Network
Patrick Garrett, Robin Park, Titus Jung, Casimir Bamberger, John R. Yates, III
Department of Chemical Physiology, The Scripps Research Institute, La Jolla, CA, USA

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A streamlined workflow for the quality control, interpretation and analysis of timsTOF Pro data: towards large-scale proteomics
A streamlined workflow for the quality control, interpretation and analysis of timsTOF Pro data: towards large-scale proteomics
Chengpin Shen1, Xianming Liu2, Xiaoxian Du2, Xiaoqing Wang1, Hebin Liu1 and Ruoyu Wu2 1 Omicsolution Co., Ltd, Shanghai, China 2 Bruker Daltonics, Shanghai, China

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CCS-centric protein identification using IM Score
CCS-centric protein identification using IM Score
Robin Park1, Patrick Garrett3, Sven Brehmer2, Titus Jung3, Vijayaraja Gnanasambandan1, Marc-Antoine Beauvais1, Sebastian Wehner2, Lennard Pfennig2, Hyunsoo Kim3, Christopher Adams1, Dennis Trede2, John R. Yates, III3, Rohan Thakur1 1Bruker Daltonics Inc., USA 2Bruker Daltonik GmbH, Bremen, Germany 3Scripps Research, San Diego, USA

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Combining the Accurate Mass and Time Tag and Ion Mobility for Label-free and Missing Peptide Analysis
Combining the Accurate Mass and Time Tag and Ion Mobility for Label-free and Missing Peptide Analysis
Robin Park1, Titus Jung 3, Sven Brehmer2, Patrick Garrett3, Vijayaraja Gnanasambandan1, Marc-Antoine Beauvais1, Casimir Bamberger3, Hyunsoo Kim3, Christopher Adams1, Dennis Trede2, John R. Yates, III3, Rohan Thakur1 1Bruker Daltonics Inc., USA 2Bruker Daltonik GmbH, Germany 3Scripps Research, San Diego, USA

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Combining Imaging and OMICs: MALDI guided SpatialOMx probes proteomic mass profiles of breast cancer tumor subpopulations
Combining Imaging and OMICs: MALDI guided SpatialOMx probes proteomic mass profiles of breast cancer tumor subpopulations
Janina Oetjen 1 , Romano Hebeler 1 , Frédéric Dewez 2 , Corinna Henkel 1 , Benjamin Balluff 2 , Ron Heeren 2
1 Bruker Daltonik GmbH, Bremen, Germany; 2 Maastricht MultiModal Molecular Imaging Institute (M4I), University of Maastricht, Maastricht, The Netherlands

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Novel MALDI-TOF MS Workflow for Ultrahigh-Throughput Screening of Different Analytes at Each Position on a Plate
Novel MALDI-TOF MS Workflow for Ultrahigh-Throughput Screening of Different Analytes at Each Position on a Plate
Sergei Dikler
Bruker Scientific, LLC, Billerica, MA

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FXa Anticoagulant Bioactive Proteins Derived from Scorpion Venom
FXa Anticoagulant Bioactive Proteins Derived from Scorpion Venom
Meng Li,1 Yuko P. Y. Lam,1 Peng Chen,2 Remy Gavard,1 Cookson K. C. Chiu,1 Christopher A. Wootton,1 Tomos E. Morgan,1 Qiong Wu,2 Mark P. Barrow,1 Hongzheng Fu,2 Peter B. O’Connor1
1Department of Chemistry, University of Warwick, Coventry, UK; 2 School of Pharmaceutical Sciences, Peking University, Beijing, China

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The Inhibition Pathways of Human Islet Amyloid Polypeptide
The Inhibition Pathways of Human Islet Amyloid Polypeptide
Yuko P. Y. Lam1; Cookson K.C. Chiu1; Christopher A. Wootton1; Ji-Inn Song1; Meng Li1; Ian Hands-Portman2; Mark P. Barrow1; and Peter B. O'Connor1
1 Department of Chemistry, University of Warwick, Coventry, UK 2 School of Life Science, University of Warwick, Coventry, UK

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2D FT-ICR MS/MS analysis of IgG1
2D FT-ICR MS/MS analysis of IgG1
Johanna Paris 1 , Tomos E. Morgan 1 , Yuko P. Y. Lam 1 Christopher A. Wootton 1 Mark André Delsuc 2 , Mark P. Barrow 1 , John O’Hara 3 , and Peter B. O’Connor 1
1. ICR lab, University of Warwick, CV4 7AL, Coventry, UK 2. 3IGBMC, Illkirch Graffenstaden , France 3. UCB, SL1 3WE, Slough, UK

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High speed untargeted 4D-lipidomics LC-MS/MS workflows with Parallel Accumulation Serial Fragmentation (PASEF)
High speed untargeted 4D-lipidomics LC-MS/MS workflows with Parallel Accumulation Serial Fragmentation (PASEF)
Ulrike Schweiger-Hufnagel1, Aiko Barsch1, Sven W. Meyer1
1Bruker Daltonik GmbH, 28359 Bremen, Germany

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TMT Quantification for Shotgun Proteomics on a Trapped-Ion-Mobility quadrupole-Time-Of- Flight mass spectrometer (TIMS-QTOF) powered by Parallel-Accumulation and Serial- Fragmentation (PASEF)
TMT Quantification for Shotgun Proteomics on a Trapped-Ion-Mobility quadrupole-Time-Of- Flight mass spectrometer (TIMS-QTOF) powered by Parallel-Accumulation and Serial- Fragmentation (PASEF)
Matt Willetts1, Shourjo Ghose1 Heiner Koch2, Scarlet Koch2, Markus Lubeck2, Gary Kruppa1
1Bruker Daltonics, Billerica, MA, USA 2Bruker Daltonik GmbH, 28359 Bremen, Germany

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Applying Trapped Ion Mobility Separation (TIMS) in combination with Parallel Accumulation Serial Fragmentation (PASEF) for analysis of lipidomics samples
Applying Trapped Ion Mobility Separation (TIMS) in combination with Parallel Accumulation Serial Fragmentation (PASEF) for analysis of lipidomics samples
Sebastian Götz1, Sven W Meyer1,Ulrike Schweiger-Hufnagel1,Aiko Barsch1, Ningombam Sanjib Meitei2
1Bruker, Bremen, Germany 2PREMIER Biosoft, Indore, India

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Results 1-20 of 24
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